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NAT10 is upregulated in hepatocellular carcinoma and enhances mutant p53 activity

BACKGROUND: N-acetyltransferase 10 (NAT10) is a histone acetyltransferase which is involved in a wide range of cellular processes. Recent evidences indicate that NAT10 is involved in the development of human cancers. Previous study showed that NAT10 acetylates the tumor suppressor p53 and regulates...

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Detalles Bibliográficos
Autores principales: Li, Qijiong, Liu, Xiaofeng, Jin, Kemin, Lu, Min, Zhang, Chunfeng, Du, Xiaojuan, Xing, Baocai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579925/
https://www.ncbi.nlm.nih.gov/pubmed/28859621
http://dx.doi.org/10.1186/s12885-017-3570-4