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Ancient human miRNAs are more likely to have broad functions and disease associations than young miRNAs
BACKGROUND: microRNAs (miRNAs) are essential to the regulation of gene expression in eukaryotes, and improper expression of miRNAs contributes to hundreds of diseases. Despite the essential functions of miRNAs, the evolutionary dynamics of how they are integrated into existing gene regulatory and fu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579935/ https://www.ncbi.nlm.nih.gov/pubmed/28859623 http://dx.doi.org/10.1186/s12864-017-4073-z |