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Leucine aminopeptidase may contribute to the intrinsic resistance of cancer cells toward cisplatin as revealed by an ultrasensitive fluorescent probe

Cisplatin, a typical anticancer drug, is often used to treat different cancers, and leucine aminopeptidase (LAP) is known to be widely distributed in organisms from bacteria to humans, including various cancer cells. However, cancer cells display different intrinsic or acquired resistance toward cis...

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Detalles Bibliográficos
Autores principales: Gong, Qiuyu, Shi, Wen, Li, Lihong, Ma, Huimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580032/
https://www.ncbi.nlm.nih.gov/pubmed/28966770
http://dx.doi.org/10.1039/c5sc03600c