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The association between Alu hypomethylation and severity of type 2 diabetes mellitus

BACKGROUND: Cellular senescence due to genomic instability is believed to be one of the mechanisms causing health problems in diabetes mellitus (DM). Low methylation levels of Alu elements or Alu hypomethylation, an epigenomic event causing genomic instability, were commonly found in aging people an...

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Detalles Bibliográficos
Autores principales: Thongsroy, Jirapan, Patchsung, Maturada, Mutirangura, Apiwat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580285/
https://www.ncbi.nlm.nih.gov/pubmed/28883893
http://dx.doi.org/10.1186/s13148-017-0395-6