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Puzzles in modern biology. V. Why are genomes overwired?

Many factors affect eukaryotic gene expression. Transcription factors, histone codes, DNA folding, and noncoding RNA modulate expression. Those factors interact in large, broadly connected regulatory control networks. An engineer following classical principles of control theory would design a simple...

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Detalles Bibliográficos
Autor principal: Frank, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580404/
https://www.ncbi.nlm.nih.gov/pubmed/28928947
http://dx.doi.org/10.12688/f1000research.11911.2