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Viral Ubiquitin Ligase Stimulates Selective Host MicroRNA Expression by Targeting ZEB Transcriptional Repressors

Infection with herpes simplex virus-1 (HSV-1) brings numerous changes in cellular gene expression. Levels of most host mRNAs are reduced, limiting synthesis of host proteins, especially those involved in antiviral defenses. The impact of HSV-1 on host microRNAs (miRNAs), an extensive network of shor...

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Detalles Bibliográficos
Autores principales: Lutz, Gabriel, Jurak, Igor, Kim, Eui Tae, Kim, Ju Youn, Hackenberg, Michael, Leader, Andrew, Stoller, Michelle L., Fekete, Donna M., Weitzman, Matthew D., Coen, Donald M., Wilson, Angus C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580467/
https://www.ncbi.nlm.nih.gov/pubmed/28783105
http://dx.doi.org/10.3390/v9080210