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Inhibitors of Deubiquitinating Enzymes Block HIV-1 Replication and Augment the Presentation of Gag-Derived MHC-I Epitopes

In recent years it has been well established that two major constituent parts of the ubiquitin proteasome system (UPS)—the proteasome holoenzymes and a number of ubiquitin ligases—play a crucial role, not only in virus replication but also in the regulation of the immunogenicity of human immunodefic...

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Detalles Bibliográficos
Autores principales: Setz, Christian, Friedrich, Melanie, Rauch, Pia, Fraedrich, Kirsten, Matthaei, Alina, Traxdorf, Maximilian, Schubert, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580479/
https://www.ncbi.nlm.nih.gov/pubmed/28805676
http://dx.doi.org/10.3390/v9080222