Statistically robust methylation calling for whole-transcriptome bisulfite sequencing reveals distinct methylation patterns for mouse RNAs

Cytosine-5 RNA methylation plays an important role in several biologically and pathologically relevant processes. However, owing to methodological limitations, the transcriptome-wide distribution of this mark has remained largely unknown. We previously established RNA bisulfite sequencing as a metho...

Descripción completa

Detalles Bibliográficos
Autores principales: Legrand, Carine, Tuorto, Francesca, Hartmann, Mark, Liebers, Reinhard, Jacob, Dominik, Helm, Mark, Lyko, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580717/
https://www.ncbi.nlm.nih.gov/pubmed/28684555
http://dx.doi.org/10.1101/gr.210666.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580717/
https://www.ncbi.nlm.nih.gov/pubmed/28684555
http://dx.doi.org/10.1101/gr.210666.116

Ejemplares similares