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Assembly and analysis of 100 full MHC haplotypes from the Danish population

Genes in the major histocompatibility complex (MHC, also known as HLA) play a critical role in the immune response and variation within the extended 4-Mb region shows association with major risks of many diseases. Yet, deciphering the underlying causes of these associations is difficult because the...

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Detalles Bibliográficos
Autores principales: Jensen, Jacob M., Villesen, Palle, Friborg, Rune M., Mailund, Thomas, Besenbacher, Søren, Schierup, Mikkel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580718/
https://www.ncbi.nlm.nih.gov/pubmed/28774965
http://dx.doi.org/10.1101/gr.218891.116