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Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank

Genetic discovery from the multitude of phenotypes extractable from routine healthcare data can transform our understanding of the human phenome and accelerate progress towards precision medicine. However, a critical question when analysing high-dimensional and heterogeneous data is how to best inte...

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Detalles Bibliográficos
Autores principales: Cortes, Adrian, Dendrou, Calliope A., Motyer, Allan, Jostins, Luke, Vukcevic, Damjan, Dilthey, Alexander, Donnelly, Peter, Leslie, Stephen, Fugger, Lars, McVean, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580804/
https://www.ncbi.nlm.nih.gov/pubmed/28759005
http://dx.doi.org/10.1038/ng.3926