Upregulation of CX3CL1 mediated by NF-κB activation in dorsal root ganglion contributes to peripheral sensitization and chronic pain induced by oxaliplatin administration

Painful peripheral neuropathy is a severe side effect in oxaliplatin therapy that compromises cancer patients' quality of life. However, its underlying pathogenic mechanisms remain largely unknown. Here, we found that intraperitoneal consecutive administration of oxaliplatin significantly incre...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Zhang, Xin-Sheng, Tao, Rong, Zhang, Jie, Liu, Lin, Jiang, Ying-Hai, Ma, Song-He, Song, Lin-Xia, Xia, Ling-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580849/
https://www.ncbi.nlm.nih.gov/pubmed/28849713
http://dx.doi.org/10.1177/1744806917726256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580849/
https://www.ncbi.nlm.nih.gov/pubmed/28849713
http://dx.doi.org/10.1177/1744806917726256

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