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Cardiolipin mediates membrane and channel interactions of the mitochondrial TIM23 protein import complex receptor Tim50

The phospholipid cardiolipin mediates the functional interactions of proteins that reside within energy-conserving biological membranes. However, the molecular basis by which this lipid performs this essential cellular role is not well understood. We address this role of cardiolipin using the multis...

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Detalles Bibliográficos
Autores principales: Malhotra, Ketan, Modak, Arnab, Nangia, Shivangi, Daman, Tyler H., Gunsel, Umut, Robinson, Victoria L., Mokranjac, Dejana, May, Eric R., Alder, Nathan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580885/
https://www.ncbi.nlm.nih.gov/pubmed/28879236
http://dx.doi.org/10.1126/sciadv.1700532