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Post-translational Control of Intracellular Pathogen Sensing Pathways

Mammalian cells recognize virus-derived nucleic acids using a defined set of intracellular sensors including the DNA sensors cyclic GMP–AMP (cGAMP) synthase (cGAS) and interferon gamma (IFNγ)-inducible protein 16 (IFI16) as well as viral RNA receptors of the retinoic acid-inducible gene I (RIG-I)-li...

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Detalles Bibliográficos
Autores principales: Chiang, Cindy, Gack, Michaela U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580928/
https://www.ncbi.nlm.nih.gov/pubmed/27863906
http://dx.doi.org/10.1016/j.it.2016.10.008