Triple DMARD treatment in early rheumatoid arthritis modulates synovial T cell activation and plasmablast/plasma cell differentiation pathways

OBJECTIVES: This study sought to investigate the genome-wide transcriptional effects of a combination of disease modifying anti-rheumatic drugs (tDMARD; methotrexate, sulfasalazine and hydroxychloroquine) in synovial tissues obtained from early rheumatoid arthritis (RA) patients. While combination D...

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Detalles Bibliográficos
Autores principales: Walsh, Alice M., Wechalekar, Mihir D., Guo, Yanxia, Yin, Xuefeng, Weedon, Helen, Proudman, Susanna M., Smith, Malcolm D., Nagpal, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580991/
https://www.ncbi.nlm.nih.gov/pubmed/28863153
http://dx.doi.org/10.1371/journal.pone.0183928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580991/
https://www.ncbi.nlm.nih.gov/pubmed/28863153
http://dx.doi.org/10.1371/journal.pone.0183928

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