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Nurse-like cells promote CLL survival through LFA-3/CD2 interactions

In the tumoral micro-environment (TME) of chronic lymphocytic leukemia (CLL), nurse-like cells (NLC) are tumor-associated macrophages which play a critical role in the survival and chemoresistance of tumoral cells. This pro-survival activity is known to involve soluble factors, but few data are avai...

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Detalles Bibliográficos
Autores principales: Boissard, Frédéric, Tosolini, Marie, Ligat, Laetitia, Quillet-Mary, Anne, Lopez, Frederic, Fournié, Jean-Jacques, Ysebaert, Loic, Poupot, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581024/
https://www.ncbi.nlm.nih.gov/pubmed/28881725
http://dx.doi.org/10.18632/oncotarget.13660