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Adult T cell leukemia aggressivenness correlates with loss of both 5-hydroxymethylcytosine and TET2 expression

Mutations in TET2, encoding one of the TET members responsible for the conversion of DNA cytosine methylation to hydroxymethylation (5-hmc), have been recently described in Human T-lymphotropic virus type 1-associated adult T-cell leukemia/lymphoma (ATLL). However, neither the amount of genomic 5-hm...

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Detalles Bibliográficos
Autores principales: Marçais, Ambroise, Waast, Laetitia, Bruneau, Julie, Hanssens, Katia, Asnafi, Vahid, Gaulard, Philippe, Suarez, Felipe, Dubreuil, Patrice, Gessain, Antoine, Hermine, Olivier, Pique, Claudine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581026/
https://www.ncbi.nlm.nih.gov/pubmed/28881727
http://dx.doi.org/10.18632/oncotarget.13665