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CRABP-II enhances pancreatic cancer cell migration and invasion by stabilizing interleukin 8 expression

Our previous study shows that cellular retinoic acid binding protein II (CRABP-II) is overexpressed in pancreatic ductal adenocarcinoma (PDAC) and pre-cancerous lesions, but not detected in normal pancreatic tissues. In this study, we show that deletion of CRABP-II in PDAC cells by CRISPR/Cas9 does...

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Detalles Bibliográficos
Autores principales: Yu, Shuiliang, Parameswaran, Neetha, Li, Ming, Wang, Yiwei, Jackson, Mark W., Liu, Huiping, Xin, Wei, Zhou, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581040/
https://www.ncbi.nlm.nih.gov/pubmed/28881741
http://dx.doi.org/10.18632/oncotarget.14194