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MM-BMSCs induce naïve CD4+ T lymphocytes dysfunction through fibroblast activation protein α
BACKGROUND: The tumor microenvironment plays a major role in multiple myelomas (MM). MM-BMSCs (bone marrow mesenchymal stromal cells) can support tumor growth and immune surveillance escape. On the other hand, fibroblast activation protein α, expressed by cancer stroma cells including BMSCs, has bee...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581055/ https://www.ncbi.nlm.nih.gov/pubmed/28881756 http://dx.doi.org/10.18632/oncotarget.17538 |