Transcription factor c-Rel is indispensable for generation of thymic but not of peripheral Foxp3(+) regulatory T cells

The transcription factor c-Rel has been shown to be crucial for development of regulatory T cells (Tregs). Recent studies have reported that the expression of transcription factor Helios in Foxp3(+) Tregs correlates with thymic origin of these cells (tTregs). Notably, we found that only the Helios(+...

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Detalles Bibliográficos
Autores principales: Luu, Maik, Jenike, Elena, Vachharajani, Niyati, Visekruna, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581060/
https://www.ncbi.nlm.nih.gov/pubmed/28881761
http://dx.doi.org/10.18632/oncotarget.17079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581060/
https://www.ncbi.nlm.nih.gov/pubmed/28881761
http://dx.doi.org/10.18632/oncotarget.17079

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