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Transcription factor c-Rel is indispensable for generation of thymic but not of peripheral Foxp3(+) regulatory T cells
The transcription factor c-Rel has been shown to be crucial for development of regulatory T cells (Tregs). Recent studies have reported that the expression of transcription factor Helios in Foxp3(+) Tregs correlates with thymic origin of these cells (tTregs). Notably, we found that only the Helios(+...
Autores principales: | Luu, Maik, Jenike, Elena, Vachharajani, Niyati, Visekruna, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581060/ https://www.ncbi.nlm.nih.gov/pubmed/28881761 http://dx.doi.org/10.18632/oncotarget.17079 |
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