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Toxicarioside O induces protective autophagy in a sirtuin-1-dependent manner in colorectal cancer cells

Colorectal cancer is the most common cancer. It has high morbidity and mortality worldwide, and more effective treatment strategies need to be developed. Toxicarioside O (TCO), a natural product derived from Antiaris toxicaria, has been shown to be a potential anticancer agent. However, the molecula...

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Detalles Bibliográficos
Autores principales: Huang, Yong-Hao, Sun, Yan, Huang, Feng-Ying, Li, Yue-Nan, Wang, Cai-Chun, Mei, Wen-Li, Dai, Hao-Fu, Tan, Guang-Hong, Huang, Canhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581069/
https://www.ncbi.nlm.nih.gov/pubmed/28881770
http://dx.doi.org/10.18632/oncotarget.17189