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PD-L1: a novel prognostic biomarker in head and neck squamous cell carcinoma

BACKGROUND: The PD-1 receptor and its ligands PD-L1 and PD-L2 are known to be significantly involved in T-cell regulation. Recent studies suggest that PD-L1 expression in malignant tumors contributes to an immunosuppressive microenvironment and disruption of antitumoral immune response. Drugs target...

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Detalles Bibliográficos
Autores principales: Müller, Tim, Braun, Martin, Dietrich, Dimo, Aktekin, Seher, Höft, Simon, Kristiansen, Glen, Göke, Friederike, Schröck, Andreas, Brägelmann, Johannes, Held, Stefanie A.E., Bootz, Friedrich, Brossart, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581079/
https://www.ncbi.nlm.nih.gov/pubmed/28881780
http://dx.doi.org/10.18632/oncotarget.17547