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miR-106b regulates the 5-fluorouracil resistance by targeting Zbtb7a in cholangiocarcinoma

BACKGROUND: Cholangiocarcinoma (CCA) is highly resistant to chemo-therapy, including 5-fluorouracil (5-FU) treatment. MicroRNAs are endogenous and short non-coding RNAs that can regulate multiple genes expression. Many microRNAs have shown functional roles in the chemo-resistance of tumors. Here, we...

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Detalles Bibliográficos
Autores principales: Jiao, Dechao, Yan, Yan, Shui, Shaofeng, Wu, Gang, Ren, JianZhuang, Wang, Yanli, Han, Xinwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581081/
https://www.ncbi.nlm.nih.gov/pubmed/28881782
http://dx.doi.org/10.18632/oncotarget.17577