Dectin-1 signaling inhibits osteoclastogenesis via IL-33-induced inhibition of NFATc1

Abnormal osteoclast activation contributes to osteolytic bone diseases (OBDs). It was reported that curdlan, an agonist of dectin-1, inhibits osteoclastogenesis. However, the underlying mechanisms are not fully elucidated. In this study, we found that curdlan potently inhibited RANKL-induced osteocl...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaoqing, Zhao, Yinghua, Jiang, Yuxue, Qin, Tianxue, Chen, Jintong, Chu, Xiao, Yi, Qing, Gao, Sujun, Wang, Siqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581116/
https://www.ncbi.nlm.nih.gov/pubmed/28881817
http://dx.doi.org/10.18632/oncotarget.18411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581116/
https://www.ncbi.nlm.nih.gov/pubmed/28881817
http://dx.doi.org/10.18632/oncotarget.18411

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