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APIO-EE-9 is a novel Aurora A and B antagonist that suppresses esophageal cancer growth in a PDX mouse model

Esophageal cancer (EC) is one of the most aggressive malignancies of the upper aerodigestive tract. Over the past three decades, with advances in surgical techniques and treatment, the prognosis of esophageal cancer has only slowly improved. Thus identifying novel molecular targets and developing th...

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Detalles Bibliográficos
Autores principales: Jin, Guoguo, Yao, Ke, Guo, Zhiping, Zhao, Zhenjiang, Liu, Kangdong, Liu, Fangfang, Chen, Hanyong, Gorja, Dhilli Rao, Reddy, Kanamata, Bode, Ann M., Dong, Ziming, Dong, Zigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581118/
https://www.ncbi.nlm.nih.gov/pubmed/28881819
http://dx.doi.org/10.18632/oncotarget.18508