Brain metastases in patients with non-small cell lung cancer: the role of mutated-EGFRs with an exon 19 deletion or L858R point mutation in cancer cell dissemination

Non-small cell lung cancer (NSCLC) patients tend to develop brain metastases (BM), but the link between BM occurrence and driver mutations in NSCLC is not very clear. We explored whether activating mutations of epidermal growth factor receptors (EGFRs) in exon 19 deletion or L858R predict BM in NSCL...

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Detalles Bibliográficos
Autores principales: Hsiao, Shih-Hsin, Chou, Yu-Ting, Lin, Sey-En, Hsu, Ru-Chun, Chung, Chi-Li, Kao, Yu-Rung, Liu, H. Eugene, Wu, Cheng-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581119/
https://www.ncbi.nlm.nih.gov/pubmed/28881820
http://dx.doi.org/10.18632/oncotarget.18509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581119/
https://www.ncbi.nlm.nih.gov/pubmed/28881820
http://dx.doi.org/10.18632/oncotarget.18509

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