TLR4 interaction with LPS in glioma CD133+ cancer stem cells induces cell proliferation, resistance to chemotherapy and evasion from cytotoxic T lymphocyte-induced cytolysis

Despite advances in treatment modalities, 5-year survival among glioma patients remains poor. Glioma cancer stem cells (CSCs) exhibit high tumorigenic activity and are associated with resistance to treatment and tumor recurrence. Because overexpression of toll-like receptor 4 (TLR4) correlated with...

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Detalles Bibliográficos
Autores principales: Che, Fengyuan, Yin, Jiawei, Quan, Yanchun, Xie, Xiaoli, Heng, Xueyuan, Du, Yifeng, Wang, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581125/
https://www.ncbi.nlm.nih.gov/pubmed/28881826
http://dx.doi.org/10.18632/oncotarget.18586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581125/
https://www.ncbi.nlm.nih.gov/pubmed/28881826
http://dx.doi.org/10.18632/oncotarget.18586

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