SHP2 negatively regulates HLA-ABC and PD-L1 expression via STAT1 phosphorylation in prostate cancer cells

Src homology region 2-containing protein tyrosine phosphatase 2 (SHP2) is a ubiquitous protein tyrosine phosphatase that activates the signal transduction pathways of several growth factors and cytokines. In our study, SHP2 expression was very high in prostate cancer (PCa) cell lines, and the expres...

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Detalles Bibliográficos
Autores principales: Liu, Zhuqing, Zhao, Yu, Fang, Juemin, Cui, Ran, Xiao, Yuanyuan, Xu, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581127/
https://www.ncbi.nlm.nih.gov/pubmed/28881828
http://dx.doi.org/10.18632/oncotarget.18591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581127/
https://www.ncbi.nlm.nih.gov/pubmed/28881828
http://dx.doi.org/10.18632/oncotarget.18591

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