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The novel sphingosine-1-phosphate receptors antagonist AD2900 affects lymphocyte activation and inhibits T-cell entry into the lymph nodes

Sphingolipid derivatives play key roles in immune cell migration and function. Synthetic sphingolipid analogues are used as therapeutics to intervene various inflammatory and malignant conditions. We hypothesize that different analogs have different effects on immune cells and therefore can be used...

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Detalles Bibliográficos
Autores principales: Song, Jing, Dagan, Arie, Yakhtin, Zhanna, Gatt, Shimon, Riley, Sean, Rosen, Hugh, Or, Reuven, Almogi-Hazan, Osnat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581131/
https://www.ncbi.nlm.nih.gov/pubmed/28881832
http://dx.doi.org/10.18632/oncotarget.18626