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The novel sphingosine-1-phosphate receptors antagonist AD2900 affects lymphocyte activation and inhibits T-cell entry into the lymph nodes
Sphingolipid derivatives play key roles in immune cell migration and function. Synthetic sphingolipid analogues are used as therapeutics to intervene various inflammatory and malignant conditions. We hypothesize that different analogs have different effects on immune cells and therefore can be used...
Autores principales: | Song, Jing, Dagan, Arie, Yakhtin, Zhanna, Gatt, Shimon, Riley, Sean, Rosen, Hugh, Or, Reuven, Almogi-Hazan, Osnat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581131/ https://www.ncbi.nlm.nih.gov/pubmed/28881832 http://dx.doi.org/10.18632/oncotarget.18626 |
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