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The novel Lyme borreliosis vaccine VLA15 shows broad protection against Borrelia species expressing six different OspA serotypes

We have previously shown that the Outer surface protein A (OspA) based Lyme borreliosis vaccine VLA15 induces protective immunity in mice. Herein, we report the induction of protective immunity by VLA15 with mouse models using ticks infected with B. burgdorferi (OspA serotype 1), B. afzelii (OspA se...

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Detalles Bibliográficos
Autores principales: Comstedt, Pär, Schüler, Wolfgang, Meinke, Andreas, Lundberg, Urban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581183/
https://www.ncbi.nlm.nih.gov/pubmed/28863166
http://dx.doi.org/10.1371/journal.pone.0184357