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c-FLIP and the NOXA/Mcl-1 axis participate in the synergistic effect of pemetrexed plus cisplatin in human choroidal melanoma cells

Choroidal melanoma is the most common primary malignant intraocular tumor, and very few effective therapies are available to treat it. Our study aimed to understand whether pemetrexed plus cisplatin exerts a beneficial synergistic effect in human choroidal melanoma cells and to delineate the underly...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaofei, Kong, Feng, Wang, Lei, Zhang, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581197/
https://www.ncbi.nlm.nih.gov/pubmed/28863158
http://dx.doi.org/10.1371/journal.pone.0184135