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Targeting the Type II Secretion System: Development, Optimization, and Validation of a High-Throughput Screen for the Identification of Small Molecule Inhibitors

Nosocomial pathogens that develop multidrug resistance present an increasing problem for healthcare facilities. Due to its rapid rise in antibiotic resistance, Acinetobacter baumannii is one of the most concerning gram-negative species. A. baumannii typically infects immune compromised individuals r...

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Detalles Bibliográficos
Autores principales: Waack, Ursula, Johnson, Tanya L., Chedid, Khalil, Xi, Chuanwu, Simmons, Lyle A., Mobley, Harry L. T., Sandkvist, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581314/
https://www.ncbi.nlm.nih.gov/pubmed/28894700
http://dx.doi.org/10.3389/fcimb.2017.00380