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Targeting the Type II Secretion System: Development, Optimization, and Validation of a High-Throughput Screen for the Identification of Small Molecule Inhibitors
Nosocomial pathogens that develop multidrug resistance present an increasing problem for healthcare facilities. Due to its rapid rise in antibiotic resistance, Acinetobacter baumannii is one of the most concerning gram-negative species. A. baumannii typically infects immune compromised individuals r...
Autores principales: | Waack, Ursula, Johnson, Tanya L., Chedid, Khalil, Xi, Chuanwu, Simmons, Lyle A., Mobley, Harry L. T., Sandkvist, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581314/ https://www.ncbi.nlm.nih.gov/pubmed/28894700 http://dx.doi.org/10.3389/fcimb.2017.00380 |
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