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Elution kinetics of vancomycin and gentamicin from carriers and their effects on mesenchymal stem cell proliferation: an in vitro study

BACKGROUND: Musculoskeletal infections remain a major complication in orthopedic surgery. The local delivery of antibiotics provides the high levels required to treat an infection without systemic toxicity. However, the local toxicity of antibiotic carriers to the mesenchymal stem cells, as a result...

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Detalles Bibliográficos
Autores principales: Kucera, Tomas, Ryskova, Lenka, Soukup, Tomas, Malakova, Jana, Cermakova, Eva, Mericka, Pavel, Suchanek, Jakub, Sponer, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581458/
https://www.ncbi.nlm.nih.gov/pubmed/28865450
http://dx.doi.org/10.1186/s12891-017-1737-4