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Elution kinetics of vancomycin and gentamicin from carriers and their effects on mesenchymal stem cell proliferation: an in vitro study
BACKGROUND: Musculoskeletal infections remain a major complication in orthopedic surgery. The local delivery of antibiotics provides the high levels required to treat an infection without systemic toxicity. However, the local toxicity of antibiotic carriers to the mesenchymal stem cells, as a result...
Autores principales: | Kucera, Tomas, Ryskova, Lenka, Soukup, Tomas, Malakova, Jana, Cermakova, Eva, Mericka, Pavel, Suchanek, Jakub, Sponer, Pavel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581458/ https://www.ncbi.nlm.nih.gov/pubmed/28865450 http://dx.doi.org/10.1186/s12891-017-1737-4 |
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