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Computational discovery and functional validation of novel fluoroquinolone resistance genes in public metagenomic data sets
BACKGROUND: Fluoroquinolones are broad-spectrum antibiotics used to prevent and treat a wide range of bacterial infections. Plasmid-mediated qnr genes provide resistance to fluoroquinolones in many bacterial species and are increasingly encountered in clinical settings. Over the last decade, several...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581476/ https://www.ncbi.nlm.nih.gov/pubmed/28865446 http://dx.doi.org/10.1186/s12864-017-4064-0 |