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Computational discovery and functional validation of novel fluoroquinolone resistance genes in public metagenomic data sets

BACKGROUND: Fluoroquinolones are broad-spectrum antibiotics used to prevent and treat a wide range of bacterial infections. Plasmid-mediated qnr genes provide resistance to fluoroquinolones in many bacterial species and are increasingly encountered in clinical settings. Over the last decade, several...

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Detalles Bibliográficos
Autores principales:	Boulund, Fredrik, Berglund, Fanny, Flach, Carl-Fredrik, Bengtsson-Palme, Johan, Marathe, Nachiket P., Larsson, DG Joakim, Kristiansson, Erik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581476/ https://www.ncbi.nlm.nih.gov/pubmed/28865446 http://dx.doi.org/10.1186/s12864-017-4064-0

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