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Fenfluramine Reduces [(11)C]Cimbi-36 Binding to the 5-HT(2A) Receptor in the Nonhuman Primate Brain

BACKGROUND: [(11)C]Cimbi-36 is a serotonin 2A receptor agonist positron emission tomography radioligand that has recently been examined in humans. The binding of agonist radioligand is expected to be more sensitive to endogenous neurotransmitter concentrations than antagonist radioligands. In the cu...

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Detalles Bibliográficos
Autores principales: Yang, Kai-Chun, Stepanov, Vladimir, Martinsson, Stefan, Ettrup, Anders, Takano, Akihiro, Knudsen, Gitte M, Halldin, Christer, Farde, Lars, Finnema, Sjoerd J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581490/
https://www.ncbi.nlm.nih.gov/pubmed/28911007
http://dx.doi.org/10.1093/ijnp/pyx051