Phase I study of salazosulfapyridine in combination with cisplatin and pemetrexed for advanced non‐small‐cell lung cancer

Spliced variant isoforms of CD44 (CD44v) are a marker of cancer stem cells in solid tumors. They stabilize the xCT subunit of the transporter system xc(–) and thereby promote synthesis of the antioxidant glutathione. Salazosulfapyridine (SASP) is an inhibitor of xCT and suppresses the proliferation...

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Detalles Bibliográficos
Autores principales: Otsubo, Kohei, Nosaki, Kaname, Imamura, Chiyo K., Ogata, Hiroaki, Fujita, Akitaka, Sakata, Shinya, Hirai, Fumihiko, Toyokawa, Gouji, Iwama, Eiji, Harada, Taishi, Seto, Takashi, Takenoyama, Mitsuhiro, Ozeki, Takeshi, Mushiroda, Taisei, Inada, Mieko, Kishimoto, Junji, Tsuchihashi, Kenji, Suina, Kentaro, Nagano, Osamu, Saya, Hideyuki, Nakanishi, Yoichi, Okamoto, Isamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581516/
https://www.ncbi.nlm.nih.gov/pubmed/28667792
http://dx.doi.org/10.1111/cas.13309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581516/
https://www.ncbi.nlm.nih.gov/pubmed/28667792
http://dx.doi.org/10.1111/cas.13309

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