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Development of a Novel Anti-Adhesive Vaccine Against Pseudomonas aeruginosa Targeting the C-terminal Disulfide Loop of the Pilin Protein

Type IV pili (T4P) are major virulence factors of Pseudomonas aeruginosa (P. aeruginosa) that are associated with primary adhesion, biofilm formation and twitching motility. This study focuses on the introduction of a novel biologically active subunit vaccine derived from the disulfide loop (DSL) of...

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Detalles Bibliográficos
Autores principales: Faezi, Sobhan, Bahrmand, Ahmad Reza, Mahdavi, Mehdi, Siadat, Seyed Davar, Nikokar, Iraj, Sardari, Soroush
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581551/
https://www.ncbi.nlm.nih.gov/pubmed/28890886
http://dx.doi.org/10.22088/acadpub.BUMS.6.2.4