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Synthesis, characterization, anti-ulcer action and molecular docking evaluation of novel benzimidazole-pyrazole hybrids

A series of six novel benzimidazole-pyrazole hybrid molecules was synthesized and characterized using elemental analysis (CHN) and spectroscopic methods ((1)HNMR, FT-IR). All the synthesized compounds were evaluated for their in vivo anti ulcerogenic activity using Albino rats (weighing 180–220 g)....

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Detalles Bibliográficos
Autores principales: Noor, Abida, Qazi, Neelum Gul, Nadeem, Humaira, Khan, Arif-ullah, Paracha, Rehan Zafar, Ali, Fawad, Saeed, Adil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581743/
https://www.ncbi.nlm.nih.gov/pubmed/29086868
http://dx.doi.org/10.1186/s13065-017-0314-0