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DISC1 Regulates the Proliferation and Migration of Mouse Neural Stem/Progenitor Cells through Pax5, Sox2, Dll1 and Neurog2

Background: Disrupted-in-schizophrenia 1 (DISC1) regulates neurogenesis and is a genetic risk factor for major psychiatric disorders. However, how DISC1 dysfunction affects neurogenesis and cell cycle progression at the molecular level is still unknown. Here, we investigated the role of DISC1 in reg...

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Detalles Bibliográficos
Autores principales: Wu, Qian, Tang, Weiting, Luo, Zhaohui, Li, Yi, Shu, Yi, Yue, Zongwei, Xiao, Bo, Feng, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581844/
https://www.ncbi.nlm.nih.gov/pubmed/28900388
http://dx.doi.org/10.3389/fncel.2017.00261