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Decreased Secondary Lesion Growth and Attenuated Immune Response after Traumatic Brain Injury in Tlr2/4(−/−) Mice

Danger-associated molecular patterns are released by damaged cells and trigger neuroinflammation through activation of non-specific pattern recognition receptors, e.g., toll-like receptors (TLRs). Since the role of TLR2 and 4 after traumatic brain injury (TBI) is still unclear, we examined the outco...

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Detalles Bibliográficos
Autores principales: Krieg, Sandro M., Voigt, Florian, Knuefermann, Pascal, Kirschning, Carsten Jürgen, Plesnila, Nikolaus, Ringel, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582067/
https://www.ncbi.nlm.nih.gov/pubmed/28912751
http://dx.doi.org/10.3389/fneur.2017.00455