Host population structure and treatment frequency maintain balancing selection on drug resistance

It is a truism that antimicrobial drugs select for resistance, but explaining pathogen- and population-specific variation in patterns of resistance remains an open problem. Like other common commensals, Streptococcus pneumoniae has demonstrated persistent coexistence of drug-sensitive and drug-resis...

Descripción completa

Detalles Bibliográficos
Autores principales: Cobey, Sarah, Baskerville, Edward B., Colijn, Caroline, Hanage, William, Fraser, Christophe, Lipsitch, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Life Sciences–Mathematics interface
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582124/
https://www.ncbi.nlm.nih.gov/pubmed/28835542
http://dx.doi.org/10.1098/rsif.2017.0295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582124/
https://www.ncbi.nlm.nih.gov/pubmed/28835542
http://dx.doi.org/10.1098/rsif.2017.0295

Ejemplares similares