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Class A CpG Oligonucleotide Priming Rescues Mice from Septic Shock via Activation of Platelet-Activating Factor Acetylhydrolase

Sepsis is a life-threatening, overwhelming immune response to infection with high morbidity and mortality. Inflammatory response and blood clotting are caused by sepsis, which induces serious organ damage and death from shock. As a mechanism of pathogenesis, platelet-activating factor (PAF) induces...

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Detalles Bibliográficos
Autores principales: Yamamoto, Yoshinari, Sugimura, Ryu, Watanabe, Takafumi, Shigemori, Suguru, Okajima, Takuma, Nigar, Shireen, Namai, Fu, Sato, Takashi, Ogita, Tasuku, Shimosato, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582170/
https://www.ncbi.nlm.nih.gov/pubmed/28912777
http://dx.doi.org/10.3389/fimmu.2017.01049