Paradoxical effect of IKKβ inhibition on the expression of E3 ubiquitin ligases and unloading‐induced skeletal muscle atrophy

We tested whether NF‐κB pathway is indispensable for the increase in expression of E3‐ligases and unloading‐induced muscle atrophy using IKKβ inhibitor IMD‐0354. Three groups of rats were used: nontreated control (C), 3 days of unloading/hindlimb suspension with (HS+IMD) or without (HS) IMD‐0354. Le...

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Detalles Bibliográficos
Autores principales: Belova, Svetlana P., Shenkman, Boris S., Kostrominova, Tatiana Y., Nemirovskaya, Tatiana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582258/
https://www.ncbi.nlm.nih.gov/pubmed/28839114
http://dx.doi.org/10.14814/phy2.13291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582258/
https://www.ncbi.nlm.nih.gov/pubmed/28839114
http://dx.doi.org/10.14814/phy2.13291

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