Cargando…

Paradoxical effect of IKKβ inhibition on the expression of E3 ubiquitin ligases and unloading‐induced skeletal muscle atrophy

We tested whether NF‐κB pathway is indispensable for the increase in expression of E3‐ligases and unloading‐induced muscle atrophy using IKKβ inhibitor IMD‐0354. Three groups of rats were used: nontreated control (C), 3 days of unloading/hindlimb suspension with (HS+IMD) or without (HS) IMD‐0354. Le...

Descripción completa

Detalles Bibliográficos
Autores principales:	Belova, Svetlana P., Shenkman, Boris S., Kostrominova, Tatiana Y., Nemirovskaya, Tatiana L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582258/ https://www.ncbi.nlm.nih.gov/pubmed/28839114 http://dx.doi.org/10.14814/phy2.13291

Ejemplares similares

P38α-MAPK Signaling Inhibition Attenuates Soleus Atrophy during Early Stages of Muscle Unloading
por: Belova, Svetlana P., et al.
Publicado: (2020)

Role of Pannexin 1 ATP-Permeable Channels in the Regulation of Signaling Pathways during Skeletal Muscle Unloading
por: Zaripova, Ksenia A., et al.
Publicado: (2021)

Differences in the Role of HDACs 4 and 5 in the Modulation of Processes Regulating MAFbx and MuRF1 Expression during Muscle Unloading
por: Mochalova, Ekaterina P., et al.
Publicado: (2020)

No-dependent signaling pathways in unloaded skeletal muscle
por: Shenkman, Boris S., et al.
Publicado: (2015)

The Effect of SERCA Activation on Functional Characteristics and Signaling of Rat Soleus Muscle upon 7 Days of Unloading
por: Sharlo, Kristina A., et al.
Publicado: (2023)

Atrogin-1/MAFbx mRNA expression is regulated by histone deacetylase 1 in rat soleus muscle under hindlimb unloading
por: Mochalova, Ekaterina P., et al.
Publicado: (2019)

Effect of L-Arginine on Titin Expression in Rat Soleus Muscle After Hindlimb Unloading
por: Ulanova, Anna, et al.
Publicado: (2019)

Metformin Attenuates Slow-to-Fast Fiber Shift and Proteolysis Markers Increase in Rat Soleus after 7 Days of Rat Hindlimb Unloading
por: Sharlo, Kristina A., et al.
Publicado: (2022)

Changes in the Mechanical Properties of Fast and Slow Skeletal Muscle after 7 and 21 Days of Restricted Activity in Rats
por: Tyganov, Sergey A., et al.
Publicado: (2023)

Roles of ATP and SERCA in the Regulation of Calcium Turnover in Unloaded Skeletal Muscles: Current View and Future Directions
por: Nemirovskaya, Tatiana L., et al.
Publicado: (2022)

L-arginine Supplementation Protects Exercise Performance and Structural Integrity of Muscle Fibers after a Single Bout of Eccentric Exercise in Rats
por: Lomonosova, Yulia N., et al.
Publicado: (2014)

Ubiquitin Ligases at the Heart of Skeletal Muscle Atrophy Control
por: Peris-Moreno, Dulce, et al.
Publicado: (2021)

Skeletal Muscle Denervation: Past, Present and Future
por: Kostrominova, Tatiana Y.
Publicado: (2022)

The E3 ubiquitin ligase TRIM62 and inflammation-induced skeletal muscle atrophy
por: Schmidt, Franziska, et al.
Publicado: (2014)

Various Jobs of Proteolytic Enzymes in Skeletal Muscle during Unloading: Facts and Speculations
por: Kachaeva, E. V., et al.
Publicado: (2012)

The Ubiquitin Ligase Nedd4-1 Participates in Denervation-Induced Skeletal Muscle Atrophy in Mice
por: Nagpal, Preena, et al.
Publicado: (2012)

Skeletal Muscle Activity and the Fate of Myonuclei
por: Shenkman, B.S., et al.
Publicado: (2010)

Ubiquitin Ligases in Longevity and Aging Skeletal Muscle
por: Hughes, David C., et al.
Publicado: (2022)

Global alternative splicing landscape of skeletal muscle atrophy induced by hindlimb unloading
por: Sun, Junjie, et al.
Publicado: (2021)

Oral intake of rice overexpressing ubiquitin ligase inhibitory pentapeptide prevents atrophy in denervated skeletal muscle
por: Nakao, Reiko, et al.
Publicado: (2021)

Ubiquitin-proteasome pathway in skeletal muscle atrophy
por: Pang, XiangSheng, et al.
Publicado: (2023)

Effects of Plantar Mechanical Stimulation on Anabolic and Catabolic Signaling in Rat Postural Muscle Under Short-Term Simulated Gravitational Unloading
por: Tyganov, Sergey A., et al.
Publicado: (2019)

Inhibition of Xanthine Oxidase by Allopurinol Prevents Skeletal Muscle Atrophy: Role of p38 MAPKinase and E3 Ubiquitin Ligases
por: Derbre, Frederic, et al.
Publicado: (2012)

Long Noncoding RNA lncMUMA Reverses Established Skeletal Muscle Atrophy following Mechanical Unloading
por: Zhang, Zong-Kang, et al.
Publicado: (2018)

Developmental regulation of MURF E3 ubiquitin ligases in skeletal muscle
por: Perera, Sue, et al.
Publicado: (2012)

Muscle Atrophy Induced by Mechanical Unloading: Mechanisms and Potential Countermeasures
por: Gao, Yunfang, et al.
Publicado: (2018)

NO-Dependent Mechanisms of Myosin Heavy Chain Transcription Regulation in Rat Soleus Muscle After 7-Days Hindlimb Unloading
por: Sharlo, Kristina A., et al.
Publicado: (2020)

HDAC4 Is Indispensable for Reduced Slow Myosin Expression at the Early Stage of Hindlimb Unloading in Rat Soleus Muscle
por: Paramonova, Inna I., et al.
Publicado: (2021)

Plantar mechanical stimulation attenuates protein synthesis decline in disused skeletal muscle via modulation of nitric oxide level
por: Tyganov, Sergey A., et al.
Publicado: (2021)

Molecular mechanism of unloading-mediated muscle atrophy and development of its countermeasures
por: Nikawa, Takeshi
Publicado: (2012)

An Anabolic Signaling Response of Rat Soleus Muscle to Eccentric Contractions Following Hindlimb Unloading: A Potential Role of Stretch-Activated Ion Channels
por: Tyganov, Sergey, et al.
Publicado: (2019)

A design principle underlying the paradoxical roles of E3 ubiquitin ligases
por: Lee, Daewon, et al.
Publicado: (2014)

Signature molecular changes in the skeletal muscle of hindlimb unloaded mice
por: Azeem, Muhammad, et al.
Publicado: (2021)

Identification of the Acetylation and Ubiquitin-Modified Proteome during the Progression of Skeletal Muscle Atrophy
por: Ryder, Daniel J., et al.
Publicado: (2015)

RNA sequencing (RNA-seq) analysis of gene expression provides new insights into hindlimb unloading-induced skeletal muscle atrophy
por: Cui, Qihao, et al.
Publicado: (2020)

A Prochlorperazine-Induced Decrease in Autonomous Muscle Activity during Hindlimb Unloading Is Accompanied by Preserved Slow Myosin mRNA Expression
por: Sharlo, Kristina A., et al.
Publicado: (2023)

Icaritin requires Phosphatidylinositol 3 kinase (PI3K)/Akt signaling to counteract skeletal muscle atrophy following mechanical unloading
por: ZHANG, Zong-Kang, et al.
Publicado: (2016)

Prochlorperazine Withdraws the Delayed Onset Tonic Activity of Unloaded Rat Soleus Muscle: A Pilot Study
por: Kalashnikov, Vitaliy E., et al.
Publicado: (2021)

Soy Glycinin Contains a Functional Inhibitory Sequence against Muscle-Atrophy-Associated Ubiquitin Ligase Cbl-b
por: Abe, Tomoki, et al.
Publicado: (2013)

Skeletal muscle unloading results in increased mitophagy and decreased mitochondrial biogenesis regulation
por: Leermakers, Pieter A., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_k8gemgbaqqkvgo69kirfouqhgk