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Alterations in fatty acid metabolism and sirtuin signaling characterize early type‐2 diabetic hearts of fructose‐fed rats

Despite the fact that skeletal muscle insulin resistance is the hallmark of type‐2 diabetes mellitus (T2DM), inflexibility in substrate energy metabolism has been observed in other tissues such as liver, adipose tissue, and heart. In the heart, structural and functional changes ultimately lead to di...

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Detalles Bibliográficos
Autores principales: Lou, Phing‐How, Lucchinetti, Eliana, Scott, Katrina Y., Huang, Yiming, Gandhi, Manoj, Hersberger, Martin, Clanachan, Alexander S., Lemieux, Hélène, Zaugg, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582268/
https://www.ncbi.nlm.nih.gov/pubmed/28830979
http://dx.doi.org/10.14814/phy2.13388