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Alterations in fatty acid metabolism and sirtuin signaling characterize early type‐2 diabetic hearts of fructose‐fed rats
Despite the fact that skeletal muscle insulin resistance is the hallmark of type‐2 diabetes mellitus (T2DM), inflexibility in substrate energy metabolism has been observed in other tissues such as liver, adipose tissue, and heart. In the heart, structural and functional changes ultimately lead to di...
Autores principales: | Lou, Phing‐How, Lucchinetti, Eliana, Scott, Katrina Y., Huang, Yiming, Gandhi, Manoj, Hersberger, Martin, Clanachan, Alexander S., Lemieux, Hélène, Zaugg, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582268/ https://www.ncbi.nlm.nih.gov/pubmed/28830979 http://dx.doi.org/10.14814/phy2.13388 |
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